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Title:
A manufacturing method of polymer containing a carboxyl group, its manufacturing method, a use, a supported type metal catalyst, and a penem system antibiotic intermediate
Document Type and Number:
Japanese Patent JP6227147
Kind Code:
B2
Abstract:
A polymer containing a carboxyl group, a preparation method and an application thereof, a supported catalyst and a preparation method thereof and preparation methods of a penem antibiotic intermediate are disclosed. The polymer is prepared by polymerizing three monomers with different structures. The carboxyl group-containing polymer is a cross-linked polymer, and a polymer chain contains a large number of benzene rings, which can improve the rigidity and hardness of the polymer, thus effectively improving the mechanical properties of the polymer. Meanwhile, in the polymer, the carboxyl group is used as a main functional group, and is used as a carrier to prepare, by means of a coordination reaction between the carboxyl group and a heavy metal, a supported metal catalyst which has better connection stability between the metal and the polymer. The above two factors can improve the stability of the supported metal catalyst, such that the catalyst can be recycled without losing the catalytic activity. Meanwhile, loss of a heavy metal active ingredient and production cost can be reduced.

Inventors:
Hong Hao
Liu Yuyuan
Don Chang Min
Chang Shin
James gage
Application Number:
JP2016535117A
Publication Date:
November 08, 2017
Filing Date:
September 10, 2014
Export Citation:
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Assignee:
Asimchem Laboratories (Tianjin) Company Limited
Asimchem Life Science (Tianjin) Company Limited
Tianjin Asimchem Pharmaceutical Company Limited
ASYMCHEM LABORATORIES (FUXIN) CO., LTD
JILIN ASYMCHEM LABORATORIES CO., LTD
International Classes:
C08F212/08; C07B61/00; C07D477/04; C08F8/44; C08F220/18
Domestic Patent References:
JP200838058A
Attorney, Agent or Firm:
Masayuki Masabayashi
Hayashi Ichiyoshi
Tetsuo Shiba
Iwaike Mitsuru