Title:
The many forms of 6-{difluoro [6- (1-methyl 1H-pyrazole 4- Il) [1, 2, 4] triazolo [4, 3-] [b] Pirie Dazzin - 3- Il] methyl} quinoline, a form of a hydrate, salt, and a manufacturing method
Document Type and Number:
Japanese Patent JP6239553
Kind Code:
B2
Abstract:
The invention relates to novel polymorphic and hydrate forms and salts of 6-{difluoro[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline, to methods for their preparation, to pharmaceutical compositions comprising at least one of said polymorphic or hydrate forms or salts, and to the therapeutic and/or prophylactic use of such compositions. The invention also provides new manners for preparing said compound.
Inventors:
Tom Cornelis Hortens Gobelts
Johann Elvin Edmond Berts
Karina Rays
Giulius Balter Joseph Deikens
Geeklet Karl Maria Stokbrokes
Johann Elvin Edmond Berts
Karina Rays
Giulius Balter Joseph Deikens
Geeklet Karl Maria Stokbrokes
Application Number:
JP2015099068A
Publication Date:
November 29, 2017
Filing Date:
May 14, 2015
Export Citation:
Assignee:
Janssen Pharmaceuticals N.B.
International Classes:
C07D487/04; A61K31/5025; A61K45/00; A61K48/00; A61K51/00; A61P35/00; A61P35/02; A61P43/00
Domestic Patent References:
JP5292102B2 |
Other References:
UY 30041 A1,2007年 5月31日
有機化合物結晶作製ハンドブック-原理とノウハウ-,2008年 7月25日,pp.57-79
有機化合物結晶作製ハンドブック-原理とノウハウ-,2008年 7月25日,pp.57-79
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Junko Kobayashi
Norio Omori
Yasuhito Suzuki
Eiji Katayama
Junko Kobayashi
Norio Omori
Yasuhito Suzuki