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Title:
The many forms of 6-{difluoro [6- (1-methyl 1H-pyrazole 4- Il) [1, 2, 4] triazolo [4, 3-] [b] Pirie Dazzin - 3- Il] methyl} quinoline, a form of a hydrate, salt, and a manufacturing method
Document Type and Number:
Japanese Patent JP6239553
Kind Code:
B2
Abstract:
The invention relates to novel polymorphic and hydrate forms and salts of 6-{difluoro[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline, to methods for their preparation, to pharmaceutical compositions comprising at least one of said polymorphic or hydrate forms or salts, and to the therapeutic and/or prophylactic use of such compositions. The invention also provides new manners for preparing said compound.

Inventors:
Tom Cornelis Hortens Gobelts
Johann Elvin Edmond Berts
Karina Rays
Giulius Balter Joseph Deikens
Geeklet Karl Maria Stokbrokes
Application Number:
JP2015099068A
Publication Date:
November 29, 2017
Filing Date:
May 14, 2015
Export Citation:
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Assignee:
Janssen Pharmaceuticals N.B.
International Classes:
C07D487/04; A61K31/5025; A61K45/00; A61K48/00; A61K51/00; A61P35/00; A61P35/02; A61P43/00
Domestic Patent References:
JP5292102B2
Other References:
UY 30041 A1,2007年 5月31日
有機化合物結晶作製ハンドブック-原理とノウハウ-,2008年 7月25日,pp.57-79
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Junko Kobayashi
Norio Omori
Yasuhito Suzuki