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Title:
A medical treatment target and a diagnostic target
Document Type and Number:
Japanese Patent JP6113721
Kind Code:
B2
Abstract:
The present invention provides methods and compositions for treatment, screening, diagnosis and prognosis of acute myeloid leukemia (AML), B-cell chronic lymphocytic leukemia, breast cancer, colorectal cancer, kidney cancer, head and neck cancer, lung cancer, ovarian cancer or pancreatic cancer, for monitoring the effectiveness of acute myeloid leukemia (AML), B-cell chronic lymphocytic leukemia, breast cancer, colorectal cancer, kidney cancer, head and neck cancer, lung cancer, ovarian cancer or pancreatic cancer treatment, and for drug development. The present invention also provides methods and compositions for depletion of immune cells to treat inflammatory diseases.

Inventors:
Christian Rolf
Alasdile Stamps
Application Number:
JP2014517978A
Publication Date:
April 12, 2017
Filing Date:
June 28, 2012
Export Citation:
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Assignee:
Oxford Biotoherapeutoix L.T.D.
International Classes:
A61K39/395; A61P35/02; C12Q1/68; G01N33/574
Foreign References:
US20090232822
Other References:
BLOOD,1985年,65(4),964-73
E. ORTOLAN,FUNCTIONAL ROLE AND PROGNOSTIC SIGNIFICANCE OF CD157 IN OVARIAN CARCINOMA,JOURNAL OF THE NATIONAL CANCER INSTITUTE,2010年 8月 4日,V102 N15,P1160-1177
Proc Natl Acad Sci U S A.,1994年,91(12),5325-9
Attorney, Agent or Firm:
Toru Ishikawa