Title:
The medicine constituent containing sugar chain addition polypeptide and the polypeptide concerned
Document Type and Number:
Japanese Patent JP6211418
Kind Code:
B2
Abstract:
[Problem] To provide a glycosylated polypeptide having affinity to somatostatin receptors and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least two amino acids in a somatostatin or an analogue thereof being replaced by glycosylated amino acids.
Inventors:
Hirofumi Ochiai
Taiji Shimoda
Fukae Kazuhiro
Maeda Masatoshi
Keisuke Tazuru
Kenta Yoshida
Taiji Shimoda
Fukae Kazuhiro
Maeda Masatoshi
Keisuke Tazuru
Kenta Yoshida
Application Number:
JP2013531455A
Publication Date:
October 11, 2017
Filing Date:
September 03, 2012
Export Citation:
Assignee:
Glycotechnology Institute Inc.
International Classes:
C07K14/655; A61K38/31; A61K47/61; A61P1/00; A61P1/04; A61P1/12; A61P3/10; A61P5/02; A61P19/02; A61P25/04; A61P25/28; A61P27/02; A61P27/06; A61P27/12; A61P29/00; A61P35/00; A61P43/00; C07K2/00; C07K19/00
Domestic Patent References:
| JP11514363A |
Foreign References:
| WO2009156511A1 | ||||
| WO2009153960A1 |
Other References:
斎藤晴比古,新しいソマトスタチンアナログの臨床応用,医学のあゆみ,1987年,Vol.141, No.12,p.907-909
Nishi T. et al.,糖鎖工学による医療用タンパク質の質的改善,Trends in Glycoscience and Glycotechnology,1992年,Vol.4, No.18,p.336-344
Pradayrol L. et al.,N-terminally extended somatostatin: the primary structure of somatostatin-28.,FEBS Lett.,1980年,Vol.109, No.1,p.55-58
Nishi T. et al.,糖鎖工学による医療用タンパク質の質的改善,Trends in Glycoscience and Glycotechnology,1992年,Vol.4, No.18,p.336-344
Pradayrol L. et al.,N-terminally extended somatostatin: the primary structure of somatostatin-28.,FEBS Lett.,1980年,Vol.109, No.1,p.55-58
Attorney, Agent or Firm:
Masahiro Nanjo
Ayako Seta
Ayako Seta
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