The medicine containing use of a physiological chilliness active ingredient, and such an active ingredient

Japanese Patent JP6096238

B2

The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.

Zurburg, Horst
Backz, michael
Oelt ring, Heiko
Mahinek, Arnold
Rogers, Hubert
Jim Hen, Ulrike
Zubkovsky, Thomas
Blauschweiler, Claus
Wittenberg, Jens
Siegel, Wolfgang

JP2015078666A

March 15, 2017

April 07, 2015

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SIMRISE AG

A61K31/4747; A23C11/04; A23G1/00; A23G1/30; A23G3/34; A23G4/00; A23G9/00; A23L2/00; A23L9/20; A23L27/20; A61K8/42; A61K8/49; A61K9/08; A61K31/167; A61K31/36; A61K31/4402; A61K31/443; A61K31/506; A61K47/10; A61K47/12; A61K47/14; A61K47/16; A61K47/22; A61K47/34; A61K47/44; A61P1/02; A61P11/00; A61P11/04; A61P11/14; A61P13/08; A61P13/10; A61P17/00; A61P25/04; A61P35/00; A61P43/00; A61Q5/02; A61Q5/06; A61Q7/00; A61Q9/02; A61Q11/00; A61Q13/00; A61Q17/04; A61Q19/00; A61Q19/10; C07C233/11; C07C235/38; C07D213/75; C07D317/60; C07D401/04; C07D405/12; C07D495/20; C09K3/00

JP2004510699A
JP5795107B2

Tetrahedron Letters,2000年,Vol. 41,p. 5761-5764
Indian Journal of Chemistry,2008年,Vol. 47B,p. 1559-1567
British Journal of Pharmacology,2006年,Vol. 148,p. 264-273
Molecular Pharmacology,2005年,Vol. 68, No. 2,p.518-527

Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka

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