The method and constituent for treating the illness caused by the Embellishment rope virus - Laboratorios del Doctor Esteve Sociedad Anonima

Title:

The method and constituent for treating the illness caused by the Embellishment rope virus

Document Type and Number:

Japanese Patent JP6143781

Kind Code:

B2

Abstract:

The present invention refers to methods and compositions to prevent viral entry into cells expressing the CD169/sialoadhesin surface receptor by inhibiting the coupling of the sialyllactose molecule contained in the viral membrane gangliosides to the CD169/sialoadhesin receptor. The invention also pertains to vaccine compositions based on dendritic cells loaded with an antigen of interest whereby the vaccine is provided together with a composition capable of preventing viral entry into cells expressing the CD169/sialoadhesin. Moreover, the invention relates to diagnostic and therapeutic compositions that can be specifically delivered to enveloped virions wherein the diagnostic/therapeutic agent is coupled to CD169/sialoadhesin.

Inventors:

Ischierdo Ucelos, Nuria
Clausrich, Hans-Georg
Loriate, Maiel
Martinez Picado, Javier

Application Number:

JP2014547900A

Publication Date:

June 07, 2017

Filing Date:

December 17, 2012

Export Citation:

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Assignee:

Laboratorios del Doctor Esteve Sociedad Anonima
FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA
Institution of Catalana de Reselka y Estudis Avancas

International Classes:

A61K31/7032; A61K39/12; A61K39/39; A61P31/14

Other References:

Glycoconjugate Journal,1999年,Vol.16,p.59-65
Glycobiology,2009年,Vol.19, No.4,p.344-355
Microbiologica,1985年,Vol.8, No.4,p.355-365
Cellular & Molecular Biology Letters,2004年,Vol.9,p.337-351

Attorney, Agent or Firm:

Konno Akio
Minoru Inami
Takeyasu Ito
Keisei Tamura

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