Title:
A method for dealing with gcongestive heart failure
Document Type and Number:
Japanese Patent JP6134190
Kind Code:
B2
Abstract:
The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
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Inventors:
Mark macchioni
Ralph Kelly
Beverly Laurel
Douglas Bee. Sawyer
Ralph Kelly
Beverly Laurel
Douglas Bee. Sawyer
Application Number:
JP2013078262A
Publication Date:
May 24, 2017
Filing Date:
April 04, 2013
Export Citation:
Assignee:
Accordor Therapeutics, ink.
The Brigham And Women's Hospital Incorporated
Beth Israel Deacones Medical Center, Incorporated
The Brigham And Women's Hospital Incorporated
Beth Israel Deacones Medical Center, Incorporated
International Classes:
A61K38/22; A61K38/00; C12N15/09; A61K38/18; A61K39/395; A61K48/00; A61P9/00; A61P9/04; A61P9/10; A61P43/00; C07K14/485
Other References:
Zhao,Y.,et al.,“Neuregulins Promote Survival and Growth of Cardiac Myocytes”J. Biol. Chem.,1998年 4月,Vol.273,No.17,P.10261-10269
Olivetti,G.,et al.,“APOPTOSIS IN THE FAILING HUMAN HEART”,N. Engl. J. Med. 1997年 4月,Vol.336,No.16,P.1131-1141
Sharov,V.G.,et al.,“Evidence of Cardiocyte Apoptosis in Myocardium of Dogs with Chronic Heart Failure”Am. J. Pathol.,1996年 1月,Vol.148,No.1,P.141-149
西垣和彦 外1名,心不全の成因“心不全の成因としてのアポトーシス”,医学のあゆみ,1998年12月,Vol.187,No.10,P.865-869
相川竜一,疾患の成立機序“アポトーシスと心不全”,医学のあゆみ,1998年 4月,Vol.185,No.1,P.45-48
Olivetti,G.,et al.,“APOPTOSIS IN THE FAILING HUMAN HEART”,N. Engl. J. Med. 1997年 4月,Vol.336,No.16,P.1131-1141
Sharov,V.G.,et al.,“Evidence of Cardiocyte Apoptosis in Myocardium of Dogs with Chronic Heart Failure”Am. J. Pathol.,1996年 1月,Vol.148,No.1,P.141-149
西垣和彦 外1名,心不全の成因“心不全の成因としてのアポトーシス”,医学のあゆみ,1998年12月,Vol.187,No.10,P.865-869
相川竜一,疾患の成立機序“アポトーシスと心不全”,医学のあゆみ,1998年 4月,Vol.185,No.1,P.45-48
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
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