Title:
The method for manufacture of pan-CDK inhibitor of formula (I), and the intermediate in the manufacture
Document Type and Number:
Japanese Patent JP5969993
Kind Code:
B2
Abstract:
The invention relates to a novel process for the preparation of pan-CDK inhibitors of the formula (I), and intermediates of the preparation.
Inventors:
Joachim Kruger
Jörg Grease
Ky Rovis
Jorma Hasfelt
Jörg Grease
Ky Rovis
Jorma Hasfelt
Application Number:
JP2013529628A
Publication Date:
August 17, 2016
Filing Date:
September 20, 2011
Export Citation:
Assignee:
Bayer Intellectual Property GmbH
International Classes:
C07D239/47; C07C69/78; C07C381/10
Domestic Patent References:
| JP2010530396A | ||||
| JP2009520740A |
Foreign References:
| WO2010046035A1 |
Other References:
TOMOOKA,C.S. et al,Enantioselective nitrogen transfer to sulfides from nitridomanganese(V) complexes,Helvetica Chimica Acta,2002年,Vol.85, No.11,p.3773-3784
WALKER,D.P. et al,Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity,Bioorganic & Medicinal Chemistry Letters,2009年,Vol.19, No.12,p.3253-3258
WALKER,D.P. et al,Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity,Bioorganic & Medicinal Chemistry Letters,2009年,Vol.19, No.12,p.3253-3258
Attorney, Agent or Firm:
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Hidehiko Ichikawa
Takahiro Aoki
Yoshie Sakurada
Yousuke Kawasaki
Toshikazu Imato
Yoshikazu Iwase
Yasufumi Shiroyama
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Hidehiko Ichikawa
Takahiro Aoki
Yoshie Sakurada
Yousuke Kawasaki
Toshikazu Imato
Yoshikazu Iwase
Yasufumi Shiroyama
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