Title:
キノリン化合物を含有する新規な組成物
Document Type and Number:
Japanese Patent JP4864724
Kind Code:
B2
Abstract:
A stable solid pharmaceutical composition consisting essentially of an effective amount of a salt of formula (II) together with an alkaline-reacting component maintaining the pH preferably above 8, or a salt with a divalent metal cation; and at least one pharmaceutical excipient; said salt of formula (II) being essentially stable during storage at room temperature for a period of at least 3 years. A process for stabilizing the salt of formula (II). A crystalline salt of formula (II) and a process for preparing said salt.
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Inventors:
Janson curl
Fristeds Thomas
One Man Hans
Björk Anders
Fristeds Thomas
One Man Hans
Björk Anders
Application Number:
JP2006551857A
Publication Date:
February 01, 2012
Filing Date:
February 04, 2005
Export Citation:
Assignee:
Active Biotech Abi
International Classes:
A61K31/47; A61K9/00; A61K9/16; A61K31/4706; A61K47/02; A61K47/10; A61K47/12; A61K47/32; A61K47/36; A61K47/38; A61P43/00; A61K9/20; C07D215/56
Domestic Patent References:
| JPH07252228A | 1995-10-03 | |||
| JPS57171975A | 1982-10-22 | |||
| JP2003512454A | 2003-04-02 | |||
| JP2002513006A | 2002-05-08 |
Foreign References:
| US6121287A | 2000-09-19 | |||
| US6133285A | 2000-10-17 |
Attorney, Agent or Firm:
Takakichi Hayashi