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Title:
A new tablet for gonadotropin
Document Type and Number:
Japanese Patent JP6166470
Kind Code:
B2
Abstract:
The present invention relates to a stable composition for gonadotropins. It provides a composition useful for stabilization of gonadotropins while preventing aggregation, dissociation, fragmentation and formation of oxidized species variants in solution for injection. Thus, it prevents instability of protein or polypeptide molecules caused due to aggregation or fragmentation or oxidation during or after formulation. Also, it provides a pharmaceutical composition of gonadotropins, which can be therapeutically used for the treatment of various indications either in single-dose form or in multi-dose form.

Inventors:
Tintin patel
Mukesh Mahajan
Sanjay Bond Padae
Sanjeev Kumar Mendiratta
Bat chandler
Application Number:
JP2016525079A
Publication Date:
July 19, 2017
Filing Date:
October 31, 2014
Export Citation:
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Assignee:
Cadilla health care limited
International Classes:
A61K38/24; A61K9/08; A61K47/02; A61K47/04; A61K47/10; A61K47/12; A61K47/14; A61K47/18; A61K47/20; A61K47/22; A61K47/26; A61K47/36; A61P5/24
Domestic Patent References:
JP2002521342A
JP2013532677A
JP2012527448A
Foreign References:
WO2010052879A1
Other References:
ゴルナーエフ 皮下注用150,2013年10月
日本医薬品添加剤協会,医薬品添加物辞典 2007,株式会社 薬事日報社,2007年,p.399
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima