Title:
新規のベンズアミジン誘導体、その製造方法およびそれを含む薬学組成物
Document Type and Number:
Japanese Patent JP5102781
Kind Code:
B2
Abstract:
The present invention relates to a novel benzamidine derivative, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The benzamidine derivative of the present invention effectively inhibits osteoclast differentiation at an extremely low concentration, and greatly increases the trabecular bone volume, and thus it can be advantageously used for the prevention and treatment of osteoporosis.
Inventors:
Ryu, Cheman
Lee, chin
Chin, Young
Lee, Kyon
Park, Cheehun
Fan, jonah
Ku, seguan
Lee, chin
Chin, Young
Lee, Kyon
Park, Cheehun
Fan, jonah
Ku, seguan
Application Number:
JP2008553157A
Publication Date:
December 19, 2012
Filing Date:
January 31, 2007
Export Citation:
Assignee:
DONG WHA PHARM.CO.,LTD
International Classes:
C07D277/24; A61K31/426; A61K31/454; A61K31/496; A61K31/5377; A61K31/541; A61P19/10; C07D277/20; C07D277/28; C07D277/34; C07D277/38; C07D417/06; C07D417/12
Domestic Patent References:
| JP2004537549A | ||||
| JP8508267A | ||||
| JP2002507968A |
Foreign References:
| US20050065198 | ||||
| WO2006014087A1 |
Attorney, Agent or Firm:
Kenzo Hara International Patent Office