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Title:
ヒストンデアセチラーゼ阻害剤としての新規二環式ヒドロキサメート
Document Type and Number:
Japanese Patent JP2005517007
Kind Code:
A
Abstract:
The present invention is directed to certain bicyclic hydroxamate derivatives that are inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed

Inventors:
Lee Hee Ren M.
Burner Eric Jay.
Application Number:
JP2003565954A
Publication Date:
June 09, 2005
Filing Date:
February 07, 2003
Export Citation:
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Assignee:
Axis Pharmaceuticals
International Classes:
C07D295/18; A61K31/166; A61K31/167; A61K31/18; A61K31/40; A61K31/404; A61K31/4045; A61K31/4164; A61K31/4184; A61K31/4406; A61K31/4409; A61K31/4453; A61K31/495; A61K31/5375; A61K45/00; A61P25/14; A61P35/00; A61P43/00; C07C259/10; C07C275/42; C07C311/08; C07C311/13; C07C311/21; C07C311/29; C07D207/16; C07D209/14; C07D209/18; C07D209/42; C07D211/10; C07D211/16; C07D211/22; C07D211/30; C07D211/46; C07D211/60; C07D211/62; C07D213/38; C07D213/56; C07D213/65; C07D213/81; C07D213/82; C07D233/54; C07D233/64; C07D235/18; C07D295/108; C07D295/135; C07D307/24; C07D307/68; C07D317/58; C07D317/60; C07D317/68; C07D333/24; C07D333/38; C07D401/12; C07D405/12; C12Q1/34; C12Q1/37; C12Q1/48; (IPC1-7): C07C259/10; A61K31/166; A61K31/167; A61K31/18; A61K31/40; A61K31/404; A61K31/4045; A61K31/4164; A61K31/4184; A61K31/4406; A61K31/4409; A61K31/4453; A61K31/495; A61K31/5375; A61K45/00; A61P25/14; A61P35/00; A61P43/00; C07C311/21; C07D207/16; C07D209/14; C07D209/42; C07D211/10; C07D211/30; C07D211/46; C07D211/60; C07D211/62; C07D213/56; C07D213/65; C07D233/64; C07D235/18; C07D295/18; C07D307/24; C07D401/12
Attorney, Agent or Firm:
Hatsushi Shimizu
Kazunori Hashimoto
Koichi Niimi