Title:
ブロモドメイン阻害剤としての新規の置換された二環式化合物
Document Type and Number:
Japanese Patent JP6461118
Kind Code:
B2
Abstract:
The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
Inventors:
Xuan Liu
John Frederick Quinn
Brian Cordell Duffy
Louis Fan One
Mei Xiao Wu Jiang
Gregory Scott Martin
Hua Jiao
Michael Ellis
Gregory Stephen Wagner
Peter Ronald Young
John Frederick Quinn
Brian Cordell Duffy
Louis Fan One
Mei Xiao Wu Jiang
Gregory Scott Martin
Hua Jiao
Michael Ellis
Gregory Stephen Wagner
Peter Ronald Young
Application Number:
JP2016520759A
Publication Date:
January 30, 2019
Filing Date:
June 20, 2014
Export Citation:
Assignee:
Zenith Epigenetics Ltd.
International Classes:
C07D403/14; A61K31/4184; A61K31/422; A61K31/427; A61K31/428; A61K31/437; A61K31/4439; A61K31/454; A61K31/4709; A61K31/4725; A61K31/496; A61K31/497; A61K31/498; A61K31/501; A61K31/506; A61K31/5377; A61P1/00; A61P1/04; A61P3/10; A61P5/14; A61P13/10; A61P17/06; A61P19/02; A61P19/08; A61P21/04; A61P25/00; A61P25/16; A61P25/18; A61P25/28; A61P27/02; A61P29/00; A61P31/12; A61P31/18; A61P31/20; A61P35/00; A61P35/02; A61P37/06; A61P37/08; A61P43/00; C07D405/14; C07D409/14; C07D413/04; C07D413/14; C07D417/14; C07D471/04
Domestic Patent References:
| JP2006511600A | ||||
| JP2004534010A | ||||
| JP2006522119A | ||||
| JP2004524350A | ||||
| JP2016525078A | ||||
| JP2008533151A | ||||
| JP2006528677A | ||||
| JP2016523259A |
Foreign References:
| WO2012143416A1 | ||||
| WO2011054846A1 |
Other References:
MedChemComm(2013),2012年 8月13日,Vol.4(1),p.140-144
Attorney, Agent or Firm:
Takuji Yamada
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai
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