Title:
海洋放線菌から単離した新規なチオデプシペプチド
Document Type and Number:
Japanese Patent JP3830964
Kind Code:
B2
Abstract:
The present invention is directed to a novel depsipeptide has been isolated from a new marine strain L-13-ACM2-092 belonging to the family Micromonosporaceae. Its production by aerobic fermentation under controlled conditions of the strain, and the isolation and purification of PM-93135 are described herein. The compound and the fermentation broth demonstrate significant activity against several cancer cell lines. The compound also shows activity against several gram positive bacteria.
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Inventors:
Bus, Giulia Perez
Francisco Romero, Milan
De Quesada, Seresa Garcia
Gravaros, Dolores Garcia
Francisco Romero, Milan
De Quesada, Seresa Garcia
Gravaros, Dolores Garcia
Application Number:
JP52622095A
Publication Date:
October 11, 2006
Filing Date:
April 06, 1995
Export Citation:
Assignee:
Hummalmar Ese A
International Classes:
C07K11/02; A61K38/00; C12N1/20; A61P31/04; C07K7/06; C12P1/06; C12R1/29
Domestic Patent References:
| JP517484A |
Other References:
Tetrahedron, 1967年,Vol.23, p.1535-1542
J Am Chem Soc. , 1975年 4月30日,Vol.97, No.9, p.2497-2502
J Am Chem Soc. , 1975年 4月30日,Vol.97, No.9, p.2497-2502
Attorney, Agent or Firm:
Yoshio Kawaguchi
Toru Nakamura
Takeshi Funayama
Toru Nakamura
Takeshi Funayama