Title:
ＨＭＧ−ＣＯＡ還元酵素由来のペプチド、および、前記ペプチドを含む美容または医薬組成物
Document Type and Number:
Japanese Patent JP5687204
Kind Code:
B2
Abstract:
The present invention relates to peptides derived from human HMG-CoA reductase of general formula (I): R1-(AA)n-X1-Gly-Lys-X2-(AA)p-R2, And of sequence SEQ ID No. 1 to SEQ ID No. 10. The present invention also relates to a cosmetic or pharmaceutical composition comprising at least one peptide of general formula (I), in a physiologically suitable medium. The present invention further relates to the use of this novel peptide as an active principle that activates human HMG-CoA reductase in a cosmetic composition intended to strengthen the barrier function of the skin and to stimulate epidermal differentiation. The invention further applies to a cosmetic treatment method intended to prevent and/or combat the external stresses and signs of cutaneous aging.
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Inventors:
クロード・ダル・ファッラ
ヌーア・ドムロジェ
ジャン−マリ・ボット
ヌーア・ドムロジェ
ジャン−マリ・ボット
Application Number:
JP2011542863A
Publication Date:
March 18, 2015
Filing Date:
December 23, 2009
Export Citation:
Assignee:
アイエスピー・インヴェストメンツ・インコーポレイテッド
International Classes:
C07K5/11; A61K8/64; A61K38/00; A61K38/44; A61P17/00; A61P37/08; A61P43/00; A61Q17/04; A61Q19/00; A61Q19/08
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Jitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Jitsuhiro