Title:
ペプチド
Document Type and Number:
Japanese Patent JP6792256
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a compound exhibiting sufficient proteasome inhibition activity in vivo.SOLUTION: There is provided a compound by binding a peptide consisting of 4 to 10 amino acid residues and recognized by 19S regulator to a tamoxifen compound represented by the formula (A), where R1 and r2 are each independently H or a C1-6 alkyl group or R1 and R2 bind each other to form saturated 5 to 8-membered single ring and R8 is a carboxyl group or an aminomethyl group.SELECTED DRAWING: None
Inventors:
Makoto Hasegawa
Tamio Mizukami
Makoto Tanaka
Isamu Shiina
Tamio Mizukami
Makoto Tanaka
Isamu Shiina
Application Number:
JP2016105440A
Publication Date:
November 25, 2020
Filing Date:
May 26, 2016
Export Citation:
Assignee:
School corporation Kansai Bunri General Academy
Tokyo University of Science
Tokyo University of Science
International Classes:
C07D295/088; A61K47/18; A61K47/42; A61P35/00; A61P43/00; C07K5/103; C07K7/06; C12N9/99
Domestic Patent References:
| JP2008094836A | ||||
| JP2006117648A | ||||
| JP2007246493A | ||||
| JP2013056837A |
Foreign References:
| WO2014061821A1 | ||||
| WO2015000868A1 |
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office