Title:
The pharmacy constituent for Premature ejaculation medical treatment
Document Type and Number:
Japanese Patent JP6042886
Kind Code:
B2
Abstract:
The present invention relates to a pharmaceutical composition for treating, preventing or improving premature ejaculation, which is taken on demand prior to sexual activity, the composition comprising clomipramine hydrochloride in an amount of 14 to 16 mg, preferably about 15mg, as an active ingredient. More preferably, the composition of the present invention further comprises pregelatinized starch and sodium starch glycolate. The pharmaceutical composition of the present invention can provide rapid onset of efficacy, reduce a dissolution (absorption) deviation according to the patient's gastrointestinal pH conditions and minimize side effects.
Inventors:
John Hongryul
Kwon Doo
Yvonsan
Quak Song Shin
Issone
Park Hyun Jung
You Junghwa
Kwon Doo
Yvonsan
Quak Song Shin
Issone
Park Hyun Jung
You Junghwa
Application Number:
JP2014518801A
Publication Date:
December 14, 2016
Filing Date:
June 28, 2012
Export Citation:
Assignee:
CTC Bio Inc.
International Classes:
A61K31/55; A61K47/26; A61K47/32; A61K47/36; A61P15/00
Domestic Patent References:
| JP2004536024A | ||||
| JP2007505831A |
Foreign References:
| WO2007000764A1 | ||||
| WO2009142428A1 |
Other References:
View of NCT01203202 on 2011_02_07,ClinicalTrials.gov archive,2011年 2月 7日,インターネット
改訂 医薬品添加物ハンドブック,株式会社薬事日報社,2007年 2月28日,第1刷,p.611-615, 825-831
Kim SC, Seo KK.,Efficacy and safety of fluoxetine, sertraline and clomipramine in patients with premature ejaculatio,J Urol. 1998 Feb;,1998年,159(2),p.425-427
改訂 医薬品添加物ハンドブック,株式会社薬事日報社,2007年 2月28日,第1刷,p.611-615, 825-831
Kim SC, Seo KK.,Efficacy and safety of fluoxetine, sertraline and clomipramine in patients with premature ejaculatio,J Urol. 1998 Feb;,1998年,159(2),p.425-427
Attorney, Agent or Firm:
Maeda patent office
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