Title:
polymer Desuechirusunichi -- nib -- conjugate
Document Type and Number:
Japanese Patent JP6009457
Kind Code:
B2
Abstract:
The invention relates to (among other things) polymer-des-ethyl sunitinib conjugates and related compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits advantages over des-ethyl sunitinib in unconjugated form.
Inventors:
Kozlowski, Antoni
Calvertson, Shawn M.
Shen, Xiao Ming
McManus, Samuel Pea.
Wilson, Mark A.
Calvertson, Shawn M.
Shen, Xiao Ming
McManus, Samuel Pea.
Wilson, Mark A.
Application Number:
JP2013546457A
Publication Date:
October 19, 2016
Filing Date:
December 23, 2011
Export Citation:
Assignee:
Nectar Therapeutics
International Classes:
C07D403/06; A61K31/4035; A61K47/34; A61K47/48; A61P35/00; A61P43/00; C08G65/333
Domestic Patent References:
| JP2005511540A | ||||
| JP2010514773A |
Foreign References:
| WO2010120387A1 | ||||
| WO2010091187A1 | ||||
| WO2010019233A1 | ||||
| WO2009126333A1 | ||||
| WO2009099670A1 | ||||
| WO2009073154A1 |
Other References:
PASUT G,PROTEIN, PEPTIDE AND NON-PEPTIDE DRUG PEGYLATION FOR THERAPEUTIC APPLICATION,EXPERT OPINION ON THERAPEUTIC PATENTS,英国,INFORMA HEALTHCARE,2004年 6月 1日,V14 N6,P859-894
GREENWALD RICHARD B,POLY(ETHYLENE GLYCOL) CONJUGATED DRUGS AND PRODRUGS: A COMPREHENSIVE REVIEW,CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS,米国,BEGELL HOUSE PUBLISHING INC,2000年 1月 1日,V17 N2,P101-161
GREENWALD RICHARD B,POLY(ETHYLENE GLYCOL) CONJUGATED DRUGS AND PRODRUGS: A COMPREHENSIVE REVIEW,CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS,米国,BEGELL HOUSE PUBLISHING INC,2000年 1月 1日,V17 N2,P101-161
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto