Title:
The proteoglycan degradation mutant for CNS medical treatment
Document Type and Number:
Japanese Patent JP6100142
Kind Code:
B2
Abstract:
The present disclosure relates to the preparation and deletion mutants of chondroitinase proteins and their use in methods for promoting the diffusion of therapeutic composition into tissues and their use for neurological functional recovery after central nervous system ("CNS") injury or disease.
Inventors:
Gruskin, Elliot, A.
Cagiano, Anthony, Oh.
Roy, gauze
Disouza, Rohini
Cagiano, Anthony, Oh.
Roy, gauze
Disouza, Rohini
Application Number:
JP2013233425A
Publication Date:
March 22, 2017
Filing Date:
November 11, 2013
Export Citation:
Assignee:
Accordor Therapeutics, ink.
International Classes:
C12N15/09; A61K31/00; A61K38/46; A61K45/00; A61K48/00; A61P25/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/88; A61K
Domestic Patent References:
| JP2007532094A | ||||
| JP9500011A | ||||
| JP2003500016A | ||||
| JP2002526028A | ||||
| JP2002505873A | ||||
| JP11500308A | ||||
| JP2003511071A |
Foreign References:
| WO2003031578A1 | ||||
| WO2003022882A1 | ||||
| WO2002065136A1 | ||||
| WO2002008285A1 | ||||
| WO2002082075A1 | ||||
| WO2001048014A1 |
Other References:
Nature,2002年,Vol.416,pp.636-640
Attorney, Agent or Firm:
Taro Yaguchi