Title:
新規なジベンジルアミン構造を有するピリミジン化合物及びこれを含有する医薬
Document Type and Number:
Japanese Patent JP5244095
Kind Code:
B2
Abstract:
A compound represented by the following general formula (I), wherein R 1 , R 2 , R 3 , R 4 and R 5 represent hydrogen atom, a halo(lower alkyl) group, cyano group and the like, R 6 represents an alkyl group, a cycloalkyl group and the like, R 7 , R 8 , R 9 and R 10 represent hydrogen atom, a halogen atom, a lower alkyl group, a halo(lower alkyl) group and the like, R 11 and R 12 represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl)(lower alkyl) group and the like, and R 13 represents hydrogen atom, a halogen atom, a lower alkoxy group and the like, which has potent inhibitory activity on cholesterol ester transfer protein (CETP).
Inventors:
Tsubaki Ogiya
Toru Miura
Ayumu Okuda
Toshiharu Arai
Hiroshi Yamazaki
Taro Aoki
Sandaizawa victory
Haruki Shibata
Shibuya Kimiyuki
Toru Miura
Ayumu Okuda
Toshiharu Arai
Hiroshi Yamazaki
Taro Aoki
Sandaizawa victory
Haruki Shibata
Shibuya Kimiyuki
Application Number:
JP2009510828A
Publication Date:
July 24, 2013
Filing Date:
April 10, 2008
Export Citation:
Assignee:
Kowa Co., Ltd.
International Classes:
C07D239/42; C07D401/12; C07D413/12; A61K31/505; A61K31/506; A61K31/5377; A61P3/04; A61P3/06; A61P7/02; A61P9/00; A61P9/10; A61P9/12; A61P43/00
Foreign References:
| WO2004020393A1 | 2004-03-11 | |||
| WO2006056854A1 | 2006-06-01 | |||
| WO2005100298A1 | 2005-10-27 |
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes
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