Recombinant monovalent antibody and its preparation method

Title:

Recombinant monovalent antibody and its preparation method

Document Type and Number:

Japanese Patent JP6341954

Kind Code:

B2

Abstract:

The present invention provides monovalent antibodies with a long half-life when administered in vivo, methods of making such monovalent antibodies, pharmaceutical compositions comprising such antibodies, and uses of the monovalent antibodies.

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Inventors:

Parlen Paul
Souffleman Janine
Fink Tom
Breaker willem carrel
Funde Winkel Yang He. Yeah.
Fan Berkel Patrick
Bourskens frank

Application Number:

JP2016129517A

Publication Date:

June 13, 2018

Filing Date:

June 30, 2016

Export Citation:

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Assignee:

GENMAB A/S

International Classes:

C07K16/00; A61K39/395; A61K47/68; A61P35/00; A61P37/06; C07K16/32; C12N15/09; C12P21/08

Domestic Patent References:

JP2004525620A
JP2002522076A
JP5525729B2

Foreign References:

WO2005014780A2
WO2005100605A1
WO2005047335A1
WO2005021592A2

Other References:

Molecular Immunology,2001年,Vol.38,p.1-8

Attorney, Agent or Firm:

Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Ryuichi Inoue
Masato Ozeki

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