Title:
The role of solubility uPAR in the cause of a disease of an albuminuria renal disease
Document Type and Number:
Japanese Patent JP6254125
Kind Code:
B2
Abstract:
Compositions which specifically block urokinase receptor (uPAR) in podocytes; compositions which modulate or block soluble urokinase receptor (suPAR); compositions which modulate pathways in which uP AR is associated with, protect against renal diseases or disorders. Methods of treatment in vivo involve use of one or more compositions.
Inventors:
Riser, jochen
Application Number:
JP2015162056A
Publication Date:
December 27, 2017
Filing Date:
August 19, 2015
Export Citation:
Assignee:
University of Miami
General Hospital Corporation, Dee/Bee/A Massachusetts General Hospital
General Hospital Corporation, Dee/Bee/A Massachusetts General Hospital
International Classes:
G01N33/50; G01N33/15
Domestic Patent References:
| JP2009533446A |
Foreign References:
| WO2007120693A1 |
Other References:
Biochem. Biophys. Res. Commun. 2000, Vol.278, p.440-446
Nature Medicine, Jan. 2008, Vol.14, p.55-63
Nature Medicine, Jan. 2008, Vol.14, p.55-63
Attorney, Agent or Firm:
Mamoru Ushiki
Tomoyuki Takahashi
Tomoyuki Takahashi
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