Title:
Site-specific labeling and targeted delivery of proteins for the treatment of cancer
Document Type and Number:
Japanese Patent JP6290187
Kind Code:
B2
Abstract:
The present invention relates to the formation of protein conjugates from proteins chemically modified for linkage to (1) anticancer drug pharmacophores, (2) ligands to biomarkers on cancer cell surfaces, (3) and/or another protein molecule. It provides and specifies new compositions, methods and combinations for tumor, and tumor vasculature targeting and cancer treatment.
Inventors:
Kranz, alexander
Application Number:
JP2015511804A
Publication Date:
March 07, 2018
Filing Date:
May 13, 2013
Export Citation:
Assignee:
Kranz, alexander
International Classes:
A61K38/00; A61K31/404; A61K31/506; A61K31/5377; A61K31/56; A61K31/69; A61K38/38; A61K38/40; A61K38/43; A61K38/50; A61K39/395; A61K45/00; A61K45/06; A61K47/54; A61K47/66; A61P35/00; C07K14/00
Domestic Patent References:
| JP2005526117A | ||||
| JP2011528654A |
Foreign References:
| WO2011140392A1 | ||||
| WO2011153250A1 | ||||
| WO2010140886A1 | ||||
| US20110002978 | ||||
| WO2002087497A1 |
Other References:
Org. Biomol. Chem.,2012年 5月10日,Vol.10,pp.4500-4504
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta
Satoko Tsuruta
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta
Satoko Tsuruta