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Title:
The stabilization protein constituent based on semi fluorination Alekan
Document Type and Number:
Japanese Patent JP6084987
Kind Code:
B2
Abstract:
The invention provides novel compositions of bioactive polypeptides and proteins with improved stability and shelf-life. The compositions are based on liquid vehicles selected from semifluorinated alkanes. These vehicles are remarkably effective in protecting polypeptides and proteins from degradation and/or aggregation. The compositions are useful for topical administration, e.g. into an eye, or by parenteral injection, e.g. via the subcutaneous or intramuscular route.

Inventors:
Bernhard Gunter
Bastian Taizinger
Zonnya Taizinger
Dieter Shelley
Clive Wilson
Anthony Pettigrew
Anette Futtic
Application Number:
JP2014552660A
Publication Date:
February 22, 2017
Filing Date:
January 22, 2013
Export Citation:
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Assignee:
Novalik Gamebha
International Classes:
A61K38/00; A61K9/10; A61K47/06
Domestic Patent References:
JP2009256353A
Foreign References:
WO2011073134A1
Attorney, Agent or Firm:
Kazuya Sekiguchi