Title:
β-ラクタマーゼインヒビターとしての2β-置換化-6-アルキリデンペニシラン酸誘導体
Document Type and Number:
Japanese Patent JP3866298
Kind Code:
B2
Abstract:
Compounds of formula I: wherein R1, R2, R3, R4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting beta-lactamase enzymes, for enhancing the activity of beta-lactam antibiotics, and for treating beta-lactam resistant bacterial infections in a mammal. The invention also provides pharmaceutical compositions, processes for preparing compounds of formula I, and novel intermediates useful for the synthesis of compounds of formula I.
Inventors:
Binac, Joan Dee.
Lao, Acayadi Srinivasa
Lao, Acayadi Srinivasa
Application Number:
JP53525999A
Publication Date:
January 10, 2007
Filing Date:
December 29, 1998
Export Citation:
Assignee:
Research Corporation Technologies, Incorporated
International Classes:
A61K31/43; C07D499/86; A61P31/04; C07D499/00; C07D499/04; C07D499/44; C07D499/87; C07D499/897
Domestic Patent References:
| JP61109791A | ||||
| JP57099590A | ||||
| JP55136288A | ||||
| JP64066189A | ||||
| JP7082273A | ||||
| JP62198687A | ||||
| JP58059990A |
Attorney, Agent or Firm:
Takashi Ishida
Jun Tsuruta
Fukumoto product
Masaya Nishiyama
Higuchi Souji
Jun Tsuruta
Fukumoto product
Masaya Nishiyama
Higuchi Souji