Title:
選択的に活性なエストロゲンとしての8β-置換エストラトリエン
Document Type and Number:
Japanese Patent JP2010533152
Kind Code:
A
Abstract:
The invention refers to 8²-substituted estra-1,3,5(10)-triene derivatives of general formula I
their use as pharmaceutical active ingredients, which have in vitro a higher affinity to estrogen receptor preparations from rat prostates than to estrogen receptor preparations from rat uteri and in vivo a preferential action in the ovary in comparison to the uterus, their production, their therapeutic use and pharmaceutical dispensing forms that contain the new compounds.
Inventors:
Peters, Olaf
Braoir, Nico
Temé, Ina
Prairie, katoya
Moon, Hans-Peter
Flitzemeier, Karl-Heinrich
Braoir, Nico
Temé, Ina
Prairie, katoya
Moon, Hans-Peter
Flitzemeier, Karl-Heinrich
Application Number:
JP2010515526A
Publication Date:
October 21, 2010
Filing Date:
July 11, 2008
Export Citation:
Assignee:
Bayer Schering Pharma Aktiengesellschaft
International Classes:
C07J1/00; A61K31/4535; A61K31/565; A61P1/04; A61P9/00; A61P9/10; A61P9/12; A61P13/08; A61P15/08; A61P15/12; A61P17/02; A61P17/06; A61P17/14; A61P19/02; A61P25/00; A61P29/00; A61P35/00; A61P37/02
Domestic Patent References:
| JP2003534248A | 2003-11-18 | |||
| JP2003534248A | 2003-11-18 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei