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Title:
A system and a method for a Ex vivo lung care
Document Type and Number:
Japanese Patent JP6144238
Kind Code:
B2
Abstract:
Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.

Inventors:
Fishman robert
Havenner robert
Fatai Hub Abdel
Abdel Azim Anus
Newell Scott
Bishop Tom
Himal Tamer
Chi Stanley
Taylor ronald
Harriott doug
Delemere Matthew
Murray Paul
Sullivan john
Anderson mark
Bringham Richard
Van drier michael
Hassanein Waleed
Application Number:
JP2014164178A
Publication Date:
June 07, 2017
Filing Date:
August 12, 2014
Export Citation:
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Assignee:
Transmedics Incorporated
International Classes:
A01N1/02
Domestic Patent References:
JP2008515914A
JP2004529938A
JP2001516768A
JP3074302A
JP2306901A
JP2282301A
Foreign References:
US20080017194
WO2006042138A1
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto