Title:
震えを減少させながら体温を制御するシステム
Document Type and Number:
Japanese Patent JP4787919
Kind Code:
B2
Abstract:
A method and apparatus for lowering the body temperature of a patient while reducing shivering by using a heat exchange device in combination with an alpha2-adrenoreceptor agonist, a non-opiod analgesic monoamine uptake inhibitor or neuropeptide that temporarily reduces shivering. The devices disclosed include a catheter having a heat exchange balloon thereon with heat exchange fluid circulating through the interior of the balloon. The heat exchange balloon is placed in the vasculature of a patient, and heat exchange fluid at a temperature other than the temperature of the blood in the vasculature is circulated through the interior of the balloon to add or remove heat from the blood of the patient. Various alpha2-adrenoreceptor agonistalpha2-adrenoreceptor agonists, non-opiod analgesic monoamine uptake inhibitors and neuropeptides are disclosed including dexmedetomidine, nefopam, neurotensin and anticonvulsant medications and pharmaceutically acceptable salts thereof. A control system for the control of the patient's temperature is disclosed for controlling the patient's temperature in conjunction with administering the alpha2-adrenoreceptor agonist, non-opiod analgesic monoamine uptake inhibitor or neuropeptide.
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Inventors:
De, Michael W.
McHold, Timothy Earl.
Keller, Wade A.
McHold, Timothy Earl.
Keller, Wade A.
Application Number:
JP2001514852A
Publication Date:
October 05, 2011
Filing Date:
July 26, 2000
Export Citation:
Assignee:
ZOLL Circulation,Inc.
International Classes:
A61M5/00; A61F7/00; A61F7/12; A61K31/00; A61K31/13; A61K31/135; A61K31/40; A61K31/401; A61K31/4025; A61K31/439; A61K31/451; A61K31/4515; A61K31/454; A61K31/472; A61K31/485; A61K31/496; A61K31/506; A61K31/553; A61K45/00; A61K45/06; A61M25/00; A61P25/00; A61P25/04; A61P29/00; A61P41/00; A61P43/00; A61B17/00; A61F7/02
Domestic Patent References:
| JPH02134132A | 1990-05-23 | |||
| JPS4917717B1 | 1974-05-02 |
Foreign References:
| US3425419A | 1969-02-04 | |||
| US5486208A | 1996-01-23 |
Attorney, Agent or Firm:
Hironobu Onda
Makoto Onda
Atsushi Honda
Miho Ikegami
Makoto Onda
Atsushi Honda
Miho Ikegami