Title:
The tablet for dealing with diabetes
Document Type and Number:
Japanese Patent JP6117811
Kind Code:
B2
Abstract:
Disclosed is a formulation for parenteral administration comprising insulin that comprises a pH memory between 1 to 4 or between 6 to 8 and an aprotic polar solvent, wherein the insulin is solubilized in the aprotic polar solvent, wherein the solubilized insulin comprises stable monomeric or dimeric forms of insulin or mixtures thereof, and wherein the water content of the formulation is equal to or less than 15% w/v.
Inventors:
Prestlerski Stephen
Scott Nancy
Scott Nancy
Application Number:
JP2014539160A
Publication Date:
April 19, 2017
Filing Date:
October 31, 2012
Export Citation:
Assignee:
Zeris Pharmaceuticals, Inc.
International Classes:
A61K38/28; A61K9/08; A61K38/22; A61K47/04; A61K47/10; A61K47/12; A61K47/14; A61K47/16; A61K47/18; A61K47/20; A61K47/22; A61K47/26; A61K47/30; A61P3/10
Foreign References:
| GB2119248A | ||||
| US20080248999 |
Other References:
Proc. Nat. Acad. Sci,1995年,Vol. 92,p. 1262-1266
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
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