Title:
EP4アゴニストを有効成分とする骨量低下疾患の治療剤
Document Type and Number:
Japanese Patent JP4273407
Kind Code:
B2
Abstract:
A pharmaceutical composition for topical administration for prevention and/or treatment of diseases associated with decrease in bone mass comprising an EP 4 agonist as an active ingredient. An EP 4 agonist, in which includes a compound possessing prostaglandin skeleton as a representative, possesses promoting action on bone formation, so it is useful for prevention and/or treatment of diseases associated with decrease in bone mass (bone diseases such as primary osteoporosis, secondary osteoporosis, bone metastasis of cancer, hypercalcemia, Paget's disease, bone loss and bone necrosis, postoperative osteogenesis, alternative therapy for bone grafting).
Inventors:
Toru Maruyama
Kaoru Kobayashi
Kobe Toru
Takayuki Maruyama
Hideyuki Yoshida
Akio Nishiura
Nobutaka Abe
Kaoru Kobayashi
Kobe Toru
Takayuki Maruyama
Hideyuki Yoshida
Akio Nishiura
Nobutaka Abe
Application Number:
JP2003515264A
Publication Date:
June 03, 2009
Filing Date:
July 22, 2002
Export Citation:
Assignee:
Ono Pharmaceutical Co., Ltd.
International Classes:
A61K31/559; A61K45/00; A61K47/40; C07D207/26; A61P1/02; A61P1/04; A61P1/16; A61P3/14; A61P7/02; A61P7/08; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/12; A61P15/08; A61P17/02; A61P17/14; A61P19/00; A61P19/02; A61P19/08; A61P19/10; A61P21/00; A61P25/00; A61P25/20; A61P25/28; A61P29/00; A61P31/04; A61P35/00; A61P35/04; A61P37/00; A61P37/02; A61P41/00; A61P43/00; C07C405/00
Domestic Patent References:
| JP2001181210A | ||||
| JP2001089444A | ||||
| JP2001220357A |
Attorney, Agent or Firm:
Kunihisa Landlord