Title:
A therapeutic material for severe heart failure as a myocardial / vascular regeneration device
Document Type and Number:
Japanese Patent JP6314349
Kind Code:
B2
Abstract:
Provided is an advanced heart failure treatment material, as a myocardial/cardiovascular regeneration device, that self-assembles, which can improve the universality and be used in an emergency by commercialization with no need of cell-culturing (cell-free) by controlling stem cells, and has a high therapeutic effect on the fundamental treatment of intractable cardiovascular diseases, in particular, advanced heart failure, in which not only the saving of lives but also improving the patient's quality of life (QOL) are urgent issues. The advanced heart failure treatment material of the present invention includes a pharmaceutical agent, an agent holding for the pharmaceutical agent, and a myocardial support device.
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Inventors:
Yoshiki Sawa
Shigeru Miyagawa
Fukushima May
Mitsuhiro Saito
Yoshinori Sakai
Kazuhisa Matsuda
Takayuki Maruyama
Shigeru Miyagawa
Fukushima May
Mitsuhiro Saito
Yoshinori Sakai
Kazuhisa Matsuda
Takayuki Maruyama
Application Number:
JP2014536844A
Publication Date:
April 25, 2018
Filing Date:
September 13, 2013
Export Citation:
Assignee:
National University Corporation Osaka University
NIPRO CORPORATION
Ono Pharmaceutical Co., Ltd.
NIPRO CORPORATION
Ono Pharmaceutical Co., Ltd.
International Classes:
A61L15/00; A61K9/12; A61K9/70; A61K31/4406; A61K47/34; A61K47/36; A61K47/42; A61L17/00; A61P9/00; A61P9/04; A61P9/08; A61P9/10; A61P9/12; A61P11/00; A61P43/00
Domestic Patent References:
| JP2008520748A | ||||
| JP2008500881A | ||||
| JP2004503294A |
Foreign References:
| WO2004032965A1 |
Other References:
Hirata Yoichiro et al,A synthetic prostacyclin agonist, ONO-1301, ameliorates ventricular remodeling after acute myocardia,Biomedicine & Aging Pathology,2011年,Vol.1,No.2,p90-96
Hirata Yoichiro et al,Synthetic prostacycline agonist, ONO-1301, ameliorates left ventricular dysfunction and cardiac fibr,Biomedicine & pharmacotherapy,2009年,Vol. 63, No. 10,pp. 781-6
Hayashi K et al,Modulation of anti-glomerular basement membrane nephritis in rats by ONO-1301, a non-prostanoid pros,Jpn J Pharmacol,1997年,vol.73,no.1,p73-82
Hirata Yoichiro et al,Synthetic prostacycline agonist, ONO-1301, ameliorates left ventricular dysfunction and cardiac fibr,Biomedicine & pharmacotherapy,2009年,Vol. 63, No. 10,pp. 781-6
Hayashi K et al,Modulation of anti-glomerular basement membrane nephritis in rats by ONO-1301, a non-prostanoid pros,Jpn J Pharmacol,1997年,vol.73,no.1,p73-82
Attorney, Agent or Firm:
Takuya Shindo
Nakamichi Yoshihiro
Kazuyuki Ohira
Nakamichi Yoshihiro
Kazuyuki Ohira