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Title:
The use in a 2 ring type heterocyclic compound and a cure
Document Type and Number:
Japanese Patent JP6100238
Kind Code:
B2
Abstract:
The invention relates to bicyclic heterocycle compounds of formula (I):or tautomeric or stereochemically isomeric forms, N-oxides, pharmaceutically acceptable salts or the solvates thereof; wherein R1, R2a, R2b, R3a, R3b, R5, R6, R7, R8, R9, p and E are as defined herein; to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Inventors:
Allison, Jo-An, Wolford
Steven, Howard
Ildico, maria, back
Gianni, Cesari
Christopher, Norbert, Johnson
Emiliano, Tamanini
James, Edward, Harvey, Day
Elisabetta, Chiarparin
Thomas, Daniel, Heightman
Martin, Frederickson
Charlotte, Mary, Griffith-Jones
Application Number:
JP2014505721A
Publication Date:
March 22, 2017
Filing Date:
April 20, 2012
Export Citation:
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Assignee:
ASTEX THERAPEUTICS LIMITED
International Classes:
C07D401/14; A61K31/496; A61K31/513; A61K31/5377; A61K45/00; A61P35/00; A61P43/00; C07D403/06; C07D403/14; C07D413/14; C07D471/04; C07D471/10; C07D487/10; C07D519/00
Domestic Patent References:
JP52012162A
JP2010535798A
JP2010523722A
JP2009544727A
JP2009536204A
JP2002504549A
Attorney, Agent or Firm:
Yukitaka Nakamura
Hirohito Katsunuma
Noritaka Yokota