Title:
ワクチン
Document Type and Number:
Japanese Patent JP5307859
Kind Code:
B2
Abstract:
The present invention relates to adjuvant compositions which are suitable to be used in vaccines. In particular, the adjuvant compositions of the present invention comprises a saponin and an immunostimulatory oligonucleotide, optionally with a carrier. Also provided by the present invention are vaccines comprising the adjuvants of the present invention and an antigen. Further provided are methods of manufacture of the adjuvants and vaccines of the present invention and their use as medicaments. Methods of treating an individual susceptible to or suffering from a disease by the administration of the vaccines of the present invention are also provided
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Inventors:
Friede, martin
Garcon, Natalie
Elman, Philip
Garcon, Natalie
Elman, Philip
Application Number:
JP2011169244A
Publication Date:
October 02, 2013
Filing Date:
August 02, 2011
Export Citation:
Assignee:
GlaxoSmithKline Biologicals Society Anonymous
International Classes:
A61K39/00; C12N15/09; A61K9/127; A61K31/7088; A61K39/02; A61K39/095; A61K39/10; A61K39/102; A61K39/112; A61K39/118; A61K39/12; A61K39/145; A61K39/21; A61K39/245; A61K39/25; A61K39/29; A61K39/39; A61P9/10; A61P25/28; A61P31/04; A61P31/12; A61P33/00; A61P33/02; A61P35/00; A61P37/04; A61P37/08; A61P43/00; A61K; A61P; A61P25/00; A61P31/00; A61P35/00; A61P37/00
Domestic Patent References:
| JP62255436A | ||||
| JP9506887A |
Foreign References:
| WO1999012565A1 | ||||
| WO1996033739A1 | ||||
| WO1998018810A1 |
Other References:
Biotherapy,1997年,Vol.11,No.2,p.132-139
KENSIL, C et al,KEYSTONE SYMPOSIA abstract book,1999年 4月12日,abstract 218
LEWIS,J.J. et al,Definition of tumor antigens suitable for vaccine construction,Semin Cancer Biol,1995年,Vol.6, No.6,p.321-7
KENSIL, C et al,KEYSTONE SYMPOSIA abstract book,1999年 4月12日,abstract 218
LEWIS,J.J. et al,Definition of tumor antigens suitable for vaccine construction,Semin Cancer Biol,1995年,Vol.6, No.6,p.321-7
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei