Title:
1, 2-DI(CYCLIC GROUP)SUBSTITUTED BENZENE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2006/134955
Kind Code:
A1
Abstract:
A compound represented by the general formula (1) or (100), a salt thereof or a hydrate of the compound or salt, which is excellent in cell adhesion-inhibitory effect and cell infiltration-inhibitory effect: (1) (100) wherein R10 represents a 5- to 10-membered cycloalkyl group which may be substituted by a hydroxyl group or the like, etc.; R30, R31 and R32 independently represent a hydrogen atom, etc.; R40 represents a C1-10 alkyl group which may be substituted by a hydroxyl group or the like, etc.; n represents an integer of 0, 1 or 2; X1 represents a group represented by the formula: CH or a nitrogen atom; R20, R21, R22 and R23 independently represent a hydrogen atom, etc.
Inventors:
KAWAHARA TETSUYA (JP)
KOTAKE MAKOTO (JP)
YONEDA NAOKI (JP)
HIROTA SHINSUKE (JP)
OHKURO MASAYOSHI (JP)
KOTAKE MAKOTO (JP)
YONEDA NAOKI (JP)
HIROTA SHINSUKE (JP)
OHKURO MASAYOSHI (JP)
Application Number:
PCT/JP2006/311900
Publication Date:
December 21, 2006
Filing Date:
June 14, 2006
Export Citation:
Assignee:
EISAI R&D MAN CO LTD (JP)
KAWAHARA TETSUYA (JP)
KOTAKE MAKOTO (JP)
YONEDA NAOKI (JP)
HIROTA SHINSUKE (JP)
OHKURO MASAYOSHI (JP)
KAWAHARA TETSUYA (JP)
KOTAKE MAKOTO (JP)
YONEDA NAOKI (JP)
HIROTA SHINSUKE (JP)
OHKURO MASAYOSHI (JP)
International Classes:
C07D207/08; A61K31/495; A61K31/496; A61K31/5377; A61K31/538; A61K31/54; A61P1/04; A61P11/06; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P37/02; A61P37/08; A61P43/00; C07D207/27; C07D207/404; C07D211/22; C07D211/46; C07D211/58; C07D211/62; C07D211/74; C07D211/76; C07D211/88; C07D213/64; C07D263/56; C07D265/36; C07D277/64; C07D279/12; C07D295/02; C07D295/08; C07D295/10; C07D295/12; C07D295/14; C07D295/18; C07D295/20; C07D309/14; C07D317/66; C07D319/18; C07D407/12; C07D413/12; C07D491/113
Domestic Patent References:
WO2005063705A1 | 2005-07-14 |
Foreign References:
JP2004523529A | 2004-08-05 | |||
JPH05186434A | 1993-07-27 | |||
JP2003506377A | 2003-02-18 | |||
JP2005505621A | 2005-02-24 |
Other References:
See also references of EP 1892238A4
Attorney, Agent or Firm:
Hasegawa, Yoshiki (Ginza First Bldg. 10-6, Ginza 1-chome, Chuo-k, Tokyo 61, JP)
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