1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME

Title:

1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME

Document Type and Number:

WIPO Patent Application WO/1996/004268

Kind Code:

A1

Abstract:

A 1,4-dihydropyridine compound represented by general formula (I) or a pharmacologically acceptable salt thereof, and an antiallergic, antiinflammatory, antineoplastic-resistance antagonist, or antineoplastic potentiator, each containing the same as the active ingredient. In said formula, R1 represents -COO-A-(3-pyridyl) and A represents C3-C6 linear alkylene which may have an intervening piperazine ring; R2 represents C2-C10 alkyl, alkenyl or alkynyl, substituted lower alkyl or alkenyl, or optionally substituted cycloalkyl; R3 represents the same group as R1 or -COO-R4; and R4 represents optionally substituted lower alkyl.

Inventors:

TASAKA SHIGEYUKI (JP)
MIURA TERUHISA (JP)
KIUE AKIRA (JP)
SEKI TAKETSUGU (JP)
SANO TETSURO (JP)
KAMAKURA MIE (JP)
FUJITA MASAKAZU (JP)

Application Number:

PCT/JP1995/001507

Publication Date:

February 15, 1996

Filing Date:

July 28, 1995

Export Citation:

Click for automatic bibliography generation Help

Assignee:

NIKKEN CHEMICALS CO LTD (JP)
TASAKA SHIGEYUKI (JP)
MIURA TERUHISA (JP)
KIUE AKIRA (JP)
SEKI TAKETSUGU (JP)
SANO TETSURO (JP)
KAMAKURA MIE (JP)
FUJITA MASAKAZU (JP)

International Classes:

C07D401/12; C07D401/14; C07D417/14; (IPC1-7): C07D401/12; C07D401/14; A61K31/445; A61K31/495

Foreign References:

JPS6160683A	1986-03-28
JPH0240383A	1990-02-09
JPH02240081A	1990-09-25
JPH05117235A	1993-05-14
JPH04244081A	1992-09-01

Other References: