Title:
1,4,7,10-TETRAAZACYCLODODECANE-1,4-DIACETIC ACID DERIVATIVES AS CHELATING AGENTS
Document Type and Number:
WIPO Patent Application WO1999035133
Kind Code:
A3
Abstract:
Compounds of general formula (I), in which R is hydrogen, a straight or branched or cyclic C1-C6 alkyl group, unsubstituted or substituted by 1 to 10 oxygen atoms, or a C1-C20 alkyl group, optionally interrupted by a phenylene, in its turn substituted by a straight or branched C1-C6 alkyl group, unsubstituted or substituted 1 to 3 C1-C7 groups; the aromatic group being unsubstituted or substituted by alkoxy, carboxy, sulfamoyl, hydroxyalkyl, amino groups; as well as their complexes with bi- trivalent metal ions having atomic number variable from 20 to 31, 39, 42, 43, 44, 49, or from 57 to 83, as well as their salts with anions of physiologically acceptable organic acids.
Inventors:
GEREMIA RENATO (IT)
MURRU MARCELLA (IT)
RIPA GIORGIO (IT)
VALLE VITTORIO (IT)
MURRU MARCELLA (IT)
RIPA GIORGIO (IT)
VALLE VITTORIO (IT)
Application Number:
PCT/EP1998/008330
Publication Date:
August 26, 1999
Filing Date:
December 18, 1998
Export Citation:
Assignee:
BRACCO SPA (IT)
DIBRA SPA (IT)
GEREMIA RENATO (IT)
MURRU MARCELLA (IT)
RIPA GIORGIO (IT)
VALLE VITTORIO (IT)
DIBRA SPA (IT)
GEREMIA RENATO (IT)
MURRU MARCELLA (IT)
RIPA GIORGIO (IT)
VALLE VITTORIO (IT)
International Classes:
A61B5/055; A61K49/00; A61K49/06; C07D257/02; G01R33/28; C07D487/08; C07F9/38; C07F9/6524; G01R33/44; (IPC1-7): C07D257/02; A61K49/00; G01N24/08; C07F9/38
Domestic Patent References:
| WO1995005118A1 | 1995-02-23 | |||
| WO1999005128A1 | 1999-02-04 | |||
| WO1999005145A1 | 1999-02-04 | |||
| WO1995009161A1 | 1995-04-06 | |||
| WO1989005802A1 | 1989-06-29 |
Foreign References:
| EP0872479A1 | 1998-10-21 | |||
| EP0545511A2 | 1993-06-09 | |||
| EP0481420A1 | 1992-04-22 | |||
| EP0448191A1 | 1991-09-25 | |||
| EP0299795A2 | 1989-01-18 | |||
| FR2736051A1 | 1997-01-03 |
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