Title:
18F-LABELED BIPHENYL COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/028557
Kind Code:
A1
Abstract:
A 18F-labeled biphenyl compound, an intermediate thereof, a preparation method therefor, a pharmaceutical composition thereof, and application thereof. The biphenyl compound has a significant suppression effect on PD-1 and/or PD-L1, can effectively alleviate or treat related diseases such as cancer, and can be used in PET tumor imaging technology.
Inventors:
WANG YUGUANG (CN)
ZHANG NONG (CN)
WU TIANZHI (CN)
ZHANG NONG (CN)
WU TIANZHI (CN)
Application Number:
PCT/CN2021/111076
Publication Date:
February 10, 2022
Filing Date:
August 06, 2021
Export Citation:
Assignee:
SHANGHAI MAXINOVEL PHARMACEUTICALS CO LTD (CN)
International Classes:
A61K51/08; C07C215/14; A61P35/00; C07B59/00; C07C22/04; C07C47/55; C07C213/08; C07C227/02; C07C229/22
Domestic Patent References:
| WO2016162368A1 | 2016-10-13 | |||
| WO2018195321A1 | 2018-10-25 | |||
| WO2018119221A1 | 2018-06-28 |
Foreign References:
| CN111138301A | 2020-05-12 | |||
| CN109562195A | 2019-04-02 | |||
| CN107573332A | 2018-01-12 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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