2-AMINOPYRIMIDINE COMPOUND AND USE THEREOF - UNIV SHENYANG PHARMACEUTICAL

Title:

2-AMINOPYRIMIDINE COMPOUND AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2024/099229

Kind Code:

A1

Abstract:

The present invention relates to a 2-aminopyrimidine compound as represented by general formula (I) and a pharmaceutically acceptable salt, solvate, or prodrug thereof, preparation methods therefor, and a pharmaceutical composition containing the compound, wherein R1, R2, Ar, X, Y, Z, m, and n have the meanings given in the description. The present invention further relates to a use of the compound of general formula (I) in preparation of a drug for treating and/or preventing hematological malignancies and inflammatory bowel disease.

More Like This:

WO/2003/028721	SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER
WO/2000/041697	UTILISATION OF 2-SUBSTITUTED 1,2-BENZISOTHIAZOLE DERIVATIVES AND 3-SUBSTITUTED TETRAHYDROPYRIDOPYRIMIDINONE DERIVATIVES FOR THE PROPHYLAXIS AND THERAPY OF CEREBRAL ISCHAEMIA
JP2013532164	How to Prepare Thrombin-Specific Inhibitors

Inventors:

ZHAO YANFANG (CN)
HOU YUNLEI (CN)
HAN LIANG (CN)
WEN JIAJIE (CN)
TONG MINGHUI (CN)
SHI XUAN (CN)

Application Number:

PCT/CN2023/129613

Publication Date:

May 16, 2024

Filing Date:

November 03, 2023

Export Citation:

Click for automatic bibliography generation Help

Assignee:

UNIV SHENYANG PHARMACEUTICAL (CN)
3D BIOOPTIMA (CN)

International Classes:

C07D401/12; A61K31/506; A61K31/5377; A61K31/541; A61P1/00; A61P1/04; A61P29/00; A61P35/02; C07D401/14; C07D403/12; C07D405/12; C07D413/14

Domestic Patent References:

WO2021000884A1

2021-01-07

Foreign References:

CN107074867A	2017-08-18
CN102066338A	2011-05-18
CN105939998A	2016-09-14
CN101679440A	2010-03-24
KR20150104748A	2015-09-16

Other References:

LI, YINGXIU ET AL.: "Discovery of 4-piperazinyl-2-aminopyrimidine Derivatives as Dual Inhibitors of JAK2 and FLT3", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 181, 7 August 2019 (2019-08-07), XP085857459, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2019.111590

Attorney, Agent or Firm:

CHINA SCIENCE PATENT & TRADEMARK AGENT LTD. (CN)

Download PDF:

View/Download PDF PDF Help

Previous Patent: VIRTUAL MACHINE MIGRATION METHOD, SYSTEM, DEVICE, AND STORAGE MEDIUM

Next Patent: METHOD FOR BROADCAST SECURITY COMMUNICATION, AND APPARATUS