Title:
2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION
Document Type and Number:
WIPO Patent Application WO2001081332
Kind Code:
A3
Abstract:
Methods of treating cyclooxygenase-2 mediated disorders comprising administering to a subject a therapeutically effective amount of one or more 2-fluorobenzenesulfonyl compounds corresponding to Formula (I) wherein A, R<1>, R<2>, and R<3> are as described in the specification, and novel 2-fluorobenzenesulfonyl compounds within Formula (I).
Inventors:
BROWN DAVID L (US)
GRANETO MATTHEW J (US)
LUDWIG CINDY L (US)
TALLEY JOHN J (US)
GRANETO MATTHEW J (US)
LUDWIG CINDY L (US)
TALLEY JOHN J (US)
Application Number:
PCT/US2001/012983
Publication Date:
April 04, 2002
Filing Date:
April 20, 2001
Export Citation:
Assignee:
PHARMACIA CORP (US)
BROWN DAVID L (US)
GRANETO MATTHEW J (US)
LUDWIG CINDY L (US)
TALLEY JOHN J (US)
BROWN DAVID L (US)
GRANETO MATTHEW J (US)
LUDWIG CINDY L (US)
TALLEY JOHN J (US)
International Classes:
A61K31/122; A61K31/341; A61K31/381; A61K31/415; A61K31/42; A61K31/44; A61P19/02; A61P29/00; A61P35/00; A61P43/00; C07C317/32; C07D333/40; C07C319/14; C07C319/20; C07C323/22; C07C323/56; C07D213/61; C07D231/12; C07D231/16; C07D261/08; C07D307/46; C07D307/58; C07D333/18; C07D333/38; (IPC1-7): C07D333/18; C07D231/12; C07D231/16; C07D261/08; C07D307/46; C07D213/52; A61K31/4155; A61K31/381; A61K31/341; A61K31/42; A61P29/00
Domestic Patent References:
| WO1994026731A1 | 1994-11-24 | |||
| WO1994015932A1 | 1994-07-21 | |||
| WO1999064415A1 | 1999-12-16 |
Foreign References:
| EP0927555A1 | 1999-07-07 | |||
| EP0745596A1 | 1996-12-04 |
Other References:
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; KIMURA, FUMIO ET AL: "Diphenylpyrrole derivatives as cyclooxygenase-2 inhibitors", XP002178404, retrieved from STN Database accession no. 131:82957
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