Title:
2,4-DIAMINOPHENOL DERIVATIVE, AND AGENT FOR INHIBITING AGGREGATION OF TAU AND/OR AMYLOID β
Document Type and Number:
WIPO Patent Application WO/2017/159484
Kind Code:
A1
Abstract:
[Problem] To provide an agent for inhibiting aggregation of tau and/or amyloid β. [Solution] A compound represented by formula (I) or a salt thereof. This compound is used in therapy, diagnosis, and symptom alleviation and in prevention of tauopathy and/or amyloidosis caused by Aβ aggregation.
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Inventors:
MIYASAKA TOMOHIRO (JP)
INOUE YOSHIKAZU (JP)
SUGIMOTO HACHIRO (JP)
IHARA YASUO (JP)
TAKAMI MAKO (JP)
NOBUHARA MIKA (JP)
FUJITA YUKI (JP)
INOUE YOSHIKAZU (JP)
SUGIMOTO HACHIRO (JP)
IHARA YASUO (JP)
TAKAMI MAKO (JP)
NOBUHARA MIKA (JP)
FUJITA YUKI (JP)
Application Number:
PCT/JP2017/009189
Publication Date:
September 21, 2017
Filing Date:
March 08, 2017
Export Citation:
Assignee:
THE DOSHISHA (JP)
International Classes:
C07D207/06; A61K31/085; A61K31/40; A61K31/4453; A61K31/454; A61K31/4545; A61K31/496; A61K31/5377; A61K31/55; A61P25/00; A61P25/28; A61P43/00; C07D211/14; C07D295/096; C07D487/08; C07D519/00
Domestic Patent References:
WO1998020864A2 | 1998-05-22 |
Foreign References:
JP2011518119A | 2011-06-23 | |||
DE1058514B | 1959-06-04 |
Other References:
HUIJBREGTS, M. A. J. ET AL.: "Human- Toxicological Effect and Damage Factors of Carcinogenic and Noncarcinogenic Chemicals for Life Cycle Impact Assessment", INTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT, vol. 1, no. 3, 2005, pages 181 - 244
DATABASE REGISTRY [O] 23 January 1988 (1988-01-23), retrieved from STN Database accession no. 112441-21-1
DATABASE REGISTRY [O] 16 November 1984 (1984-11-16), retrieved from STN Database accession no. 53013-44-8
DATABASE REGISTRY [O] 23 January 1988 (1988-01-23), retrieved from STN Database accession no. 112441-21-1
DATABASE REGISTRY [O] 16 November 1984 (1984-11-16), retrieved from STN Database accession no. 53013-44-8
Attorney, Agent or Firm:
MAEDA & PARTNERS (JP)
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