3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR

WIPO Patent Application WO/2019/000237

A1

Provided are pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. Provided is also use of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. Provided are also compositions comprising these compounds. Provided is also use of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

ACTON JOHN J (US)
BAO JIANMING (CN)
DENG QIAOLIN (US)
EGBERTSON MELISSA (US)
FERGUSON RONALD (US)
GAO XIAOLEI (US)
HARRISON SCOTT T (US)
HENDERSON TIMOTHY J (US)
KNOWLES SANDRA L (US)
LO MICHAEL MAN-CHU (US)
MAZZOLA ROBERT D (US)
SELYUTIN OLEG (US)
ZHANG FENGQI (US)
NA MENG (CN)
SUZUKI TAKAO (CN)

PCT/CN2017/090385

January 03, 2019

June 27, 2017

Click for automatic bibliography generation  

MERCK SHARP & DOHME (US)
MSD R & D CHINA CO LTD (CN)
ACTON JOHN J III (US)
BAO JIANMING (CN)
DENG QIAOLIN (US)
EGBERTSON MELISSA (US)
FERGUSON RONALD (US)
GAO XIAOLEI (US)
HARRISON SCOTT T (US)
HENDERSON TIMOTHY J (US)
KNOWLES SANDRA L (US)
LO MICHAEL MAN CHU (US)
MAZZOLA ROBERT D JR (US)
SELYUTIN OLEG (US)
ZHANG FENGQI (US)
NA MENG (CN)
SUZUKI TAKAO (CN)

C07D231/10; A61K31/455; A61P25/00; C07D231/02; C07D401/14

WO2009135944A1	2009-11-12
WO2011087776A1	2011-07-21
WO2013056015A1	2013-04-18
WO2013040534A1	2013-03-21

WU, FENG & ZHANG (CN)

View/Download PDF      PDF Help

Previous Patent: 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR

Next Patent: 5-(PYRIDIN-3-YL)OXAZOLE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR