3-alkyl-3-phenyl-piperidines - WARNER LAMBERT CO

Title:

3-alkyl-3-phenyl-piperidines

Document Type and Number:

WIPO Patent Application WO1998011090

Kind Code:

A3

Abstract:

The small nonpeptides of the instant invention are tachykinin antagonists. The compounds are highly selective and functional NK3 antagonists expected to be useful in the treatment of pain, depression, anxiety, panic, schizophrenia, neuralgia, addiction disorders, inflammatory diseases, gastrointestinal disorders, vascular disorders, and neuropathological disorders.

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Inventors:

CHEN MICHAEL HUAI GU (US)
CHUNG FU-ZON (US)
LEE HELEN TSENWHEI (US)

Application Number:

PCT/US1997/015443

Publication Date:

May 22, 1998

Filing Date:

September 02, 1997

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Assignee:

WARNER LAMBERT CO (US)
CHEN MICHAEL HUAI GU (US)
CHUNG FU-ZON (US)
LEE HELEN TSENWHEI (US)

International Classes:

A61P25/22; C07D211/22; C07D211/26; C07D211/48; C07D211/52; C07D309/12; C07D401/14; C07D405/06; (IPC1-7): C07D211/52; C07D211/54; C07D211/26; C07D211/58; C07D401/14; C07D309/12; A61K31/445

Domestic Patent References:

WO1997010211A1

1997-03-20

Foreign References:

EP0673928A1	1995-09-27
EP0512901A1	1992-11-11

Other References:

CHEMICAL ABSTRACTS, vol. 126, no. 21, 1997, Columbus, Ohio, US; abstract no. 277367q, HUAI G. CHEN ET AL.: "A PRACTICAL AND SCALABLE SYNTHESIS OF SR 142801" page 657; column 2;

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