Title:
3-CARBONYLAMINO-5-CYCLOPENTYL-1H-PYRAZOLE COMPOUNDS HAVING INHIBITORY ACTIVITY ON CDK2
Document Type and Number:
WIPO Patent Application WO/2020/157652
Kind Code:
A8
Abstract:
This invention relates to compounds of Formula (I), and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.
Inventors:
BEHENNA DOUGLAS CARL (US)
FREEMAN-COOK KEVIN DANIEL (US)
HOFFMAN ROBERT LOUIS (US)
NAGATA ASAKO (US)
NINKOVIC SACHA (US)
SUTTON SCOTT CHANNING (US)
FREEMAN-COOK KEVIN DANIEL (US)
HOFFMAN ROBERT LOUIS (US)
NAGATA ASAKO (US)
NINKOVIC SACHA (US)
SUTTON SCOTT CHANNING (US)
Application Number:
PCT/IB2020/050653
Publication Date:
August 19, 2021
Filing Date:
January 28, 2020
Export Citation:
Assignee:
PFIZER (US)
International Classes:
C07D231/40; A61K31/415; A61P35/00; C07D401/12; C07D401/14; C07D403/12; C07D403/14; C07D405/12; C07D405/14; C07D413/12; C07D413/14; C07D417/12; C07D417/14; C07D471/04; C07D487/04; C07D513/04
Attorney, Agent or Firm:
ZIELINSKI, Bryan C. et al. (US)
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