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Title:
4- AND 5-AMINO-$g(a), $g(b) UNSTATURATED ESTER SOLID SUPPORT TEMPLATES, METHOD OF PREPARATION AND FOR USING THE SAME
Document Type and Number:
WIPO Patent Application WO/2003/013740
Kind Code:
A1
Abstract:
A substituted $g(a), $g(b)-unsaturated ester template of the general formula (1) where: P is an insoluble substrate; n is 1 or 2; X is an atom or a functional group connecting the polymer and the linker L. having a structure such as but not limited to oxygen, ester, amide, sulfur, silicon and carbon; L is a multifunctional chemical monomer in which one functional group reacts with the polymer to form a covalent bond (X) and one other of the functional groups react with one of the R groups (R¿1?, R¿2?, R¿3?, R¿5?, or R¿6?) through a plurality of chemical reactions to provide the desired templates for further chemistry. The ester template is useful for the solid phase synthesis of heterocycle compounds.

Inventors:
LOU BOLIANG
MAJJLI ADNAN M M
Application Number:
PCT/US2001/041615
Publication Date:
February 20, 2003
Filing Date:
August 03, 2001
Export Citation:
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Assignee:
ADVANCED SYNTECH LLC (US)
International Classes:
C07B61/00; C40B40/04; C40B50/14; (IPC1-7): B05D7/00; B32B15/02; B32B17/02; B32B19/00; B32B21/02; B32B23/02; B32B27/02; C08G18/00; C08G63/48; C08G63/91
Foreign References:
US5324776A1994-06-28
US6117940A2000-09-12
Attorney, Agent or Firm:
Vanderburgh, John E. (KY, US)
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