4-AMINOPYRIDINE DERIVATIVE

WIPO Patent Application WO/2016/027780

A1

A compound represented by formula (I), or a pharmaceutically acceptable salt thereof, acts as an FGFR inhibitor. [In the formula: A represents a C6-10 arylene group or the like that may have a substituent; J represents a C3-10 nitrogen-containing non-aromatic heterocyclic group or the like that may have 1-3 substituents selected from the L group of substituents; R1, R2, and R3 represent a hydrogen atom or the like; R4 represents a C1-6 alkyl group that may have a substituent; R5 represents a hydroxy C1-6 alkyl group that may be substituted with 1-3 halogen atoms; R6, R7, R8, R9, and R10 each independently represents a hydrogen atom or the like; and the L group of substituents represents a group that comprises C1-6 alkyl groups or the like that may be substituted with 1 or 2 hydroxyl groups.]

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FUNASAKA SETSUO (JP)
OKADA TOSHIMI (JP)
NAGAO SATOSHI (JP)
OHASHI ISAO (JP)
NAKATANI YUSUKE (JP)
KAROJI YUKI (JP)

PCT/JP2015/073046

February 25, 2016

August 17, 2015

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EISAI R&D MAN CO LTD (JP)

C07D401/12; A61K31/4439; A61K31/4545; A61K31/496; A61K31/5377; A61P35/00; A61P43/00; C07D401/14; C07D417/14; C07D451/06; C07D487/08

WO2004020434A1	2004-03-11
WO2006030941A1	2006-03-23
WO2007015569A1	2007-02-08
WO2007015578A1	2007-02-08

JP2012511535A

2012-05-24

HASEGAWA Yoshiki et al. (JP)
Yoshiki Hasegawa (JP)

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