Title:
4-METHOXY-2-PHENETHYL ISOINDOLINE-1-ONE DERIVATIVE, AND COMPOSITION FOR TREATING NEUROLOGICAL DISORDERS, COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2022/065823
Kind Code:
A1
Abstract:
The present invention relates to: a novel 4-methoxy-2-phenethyl isoindoline-1-one derivative compound having the ability to promote nerve growth factor increase, the ability to promote nerve cell growth, and antineuritic activity; and a composition for preventing, alleviating and treating neurological disorders, comprising same.
Inventors:
JUNG JAEKYUNG (KR)
LEE MI KYEONG (KR)
LEE DAE HEE (KR)
LEE JAE KANG (KR)
KIM SUN YEOU (KR)
YOON DA HYE (KR)
HONG SEONG MIN (KR)
LEE MI KYEONG (KR)
LEE DAE HEE (KR)
LEE JAE KANG (KR)
KIM SUN YEOU (KR)
YOON DA HYE (KR)
HONG SEONG MIN (KR)
Application Number:
PCT/KR2021/012793
Publication Date:
March 31, 2022
Filing Date:
September 17, 2021
Export Citation:
Assignee:
CNG BIO CO LTD (KR)
NAT UNIV CHUNGBUK IND ACAD COOP FOUND (KR)
UNIV GACHON IND ACAD COOP FOUND (KR)
NAT UNIV CHUNGBUK IND ACAD COOP FOUND (KR)
UNIV GACHON IND ACAD COOP FOUND (KR)
International Classes:
C07D209/46; A23K20/132; A23L33/10; A61K31/4035; A61P9/10; A61P25/00; A61P25/28
Foreign References:
| JP2012077030A | 2012-04-19 | |||
| KR102061526B1 | 2020-01-06 | |||
| KR20140082052A | 2014-07-02 | |||
| US20090275578A1 | 2009-11-05 | |||
| KR100935615B1 | 2010-01-07 |
Other References:
ANDRADE-JORGE ERIK; SáNCHEZ-LABASTIDA LUIS A.; SORIANO-URSúA MARVIN A.; GUEVARA-SALAZAR JUAN A.; TRUJILLO-FERRARA JOS: "Isoindolines/isoindoline-1,3-diones as AChE inhibitors against Alzheimer’s disease, evaluated by an improved ultra-micro assay", MEDICINAL CHEMISTRY RESEARCH, vol. 27, no. 9, 30 July 2018 (2018-07-30), US , pages 2187 - 2198, XP036576173, ISSN: 1054-2523, DOI: 10.1007/s00044-018-2226-5
YUANYANKNER, NATURE, vol. 407, 2000, pages 802 - 809
YUANYANKNER, NATURE, vol. 407, 2000, pages 802 - 809
Attorney, Agent or Firm:
CHOI, Eun Sun (KR)
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