Title:
46508, A NOVEL HUMAN PEPTIDYL-TRNA HYDROLASE FAMILY MEMBER AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2002000859
Kind Code:
A3
Abstract:
The invention provides isolated nucleic acid molecules, designated 46508 nucleic acid molecules, which encode novel peptidyl-tRNA hydrolase members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 46508 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 46508 gene has been introduced or disrupted. The invention still further provides isolated 46508 proteins, fusion proteins, antigenic peptides and anti-46508 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
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Inventors:
GLUCKSMANN MARIA ALEXANDRIA (US)
RUDOLPH-OWEN LAURA A (US)
RUDOLPH-OWEN LAURA A (US)
Application Number:
PCT/US2001/019967
Publication Date:
July 04, 2002
Filing Date:
June 25, 2001
Export Citation:
Assignee:
MILLENNIUM PHARM INC (US)
GLUCKSMANN MARIA ALEXANDRIA (US)
RUDOLPH-OWEN LAURA A (US)
GLUCKSMANN MARIA ALEXANDRIA (US)
RUDOLPH-OWEN LAURA A (US)
International Classes:
C12N9/18; C12N15/55; (IPC1-7): C12N9/18; C12N15/55; C07K16/28; G01N33/53; G01N33/573; C12Q1/68
Domestic Patent References:
| WO1999026970A1 | 1999-06-03 | |||
| WO2001053312A1 | 2001-07-26 | |||
| WO2001083524A2 | 2001-11-08 |
Other References:
DATABASE EMBL [online] 9 April 2000 (2000-04-09), STRAUSBERG, R.: "hi93b06.x1 Soares_NFL_T_GBC_S1 Homo sapiens cDNA clone IMAGE:2979827 3' similar to SW:PTH_MYCTU P96386 PEPTIDYL-TRNA HYDROLASE ;, mRNA sequence.", XP002198075, Database accession no. AW665597
DATABASE EMBL [online] 14 June 2000 (2000-06-14), STRAUSBERG, R.: "bb75b08.y1 NIH_MGC_12 Homo sapiens cDNA clone IMAGE:3048183 5' similar to SW:PTH_MYCTU P96386 PEPTIDYL-TRNA HYDROLASE ;, mRNA sequence.", XP002198076, Database accession no. BE018096
DATABASE EMBL [online] 3 May 1999 (1999-05-03), BIRREN, B.: "Homo sapiens chromosome 9 clone RP11-94E8 map 9, *** SEQUENCING IN PROGRESS ***, 7 unordered pieces.", XP002198077, Database accession no. AC007430
DATABASE EMBL [online] 14 June 2000 (2000-06-14), STRAUSBERG, R.: "bb75b08.y1 NIH_MGC_12 Homo sapiens cDNA clone IMAGE:3048183 5' similar to SW:PTH_MYCTU P96386 PEPTIDYL-TRNA HYDROLASE ;, mRNA sequence.", XP002198076, Database accession no. BE018096
DATABASE EMBL [online] 3 May 1999 (1999-05-03), BIRREN, B.: "Homo sapiens chromosome 9 clone RP11-94E8 map 9, *** SEQUENCING IN PROGRESS ***, 7 unordered pieces.", XP002198077, Database accession no. AC007430
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