5-HT1F AGONISTS - LILLY CO ELI

Title:

5-HT1F AGONISTS

Document Type and Number:

WIPO Patent Application WO2000000490

Kind Code:

A3

Abstract:

The present invention relates to a compound of formula (I); or a pharmaceutical acid addition salt thereof; which are useful for activating 5-HT1F receptors and inhibiting neuronal protein extravasation in a mammal.

More Like This:

WO/2022/144416

NOVEL COMPOUNDS WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF

Inventors:

KRUSHINSKI JOSEPH HERMAN JR (US)
ROCCO VINCENT PATRICK (US)
SCHAUS JOHN MEHNERT (US)

Application Number:

PCT/US1999/014502

Publication Date:

April 17, 2003

Filing Date:

June 24, 1999

Export Citation:

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Assignee:

LILLY CO ELI (US)
KRUSHINSKI JOSEPH HERMAN JR (US)
ROCCO VINCENT PATRICK (US)
SCHAUS JOHN MEHNERT (US)

International Classes:

C07D401/04; (IPC1-7): C07D471/04; A61K31/445

Domestic Patent References:

WO1994014770A1	1994-07-07
WO1994024127A1	1994-10-27
WO1991018897A1	1991-12-12
WO1995032196A1	1995-11-30

Foreign References:

EP0313397A1	1989-04-26
EP0303506A2	1989-02-15
EP0733628A1	1996-09-25
EP0714894A1	1996-06-05

Other References:

JOHNSON K W ET AL: "INHIBITION OF NEUROGENIC PROTEIN EXTRAVASATION IN THE DURA VIA 5 -HT1F RECEPTOR ACTIVATION-IMPLICATIONS TO MIGRAINE THERAPY", SOCIETY FOR NEUROSCIENCE ABSTRACTS, vol. 22, no. 1/03, 1 November 1996 (1996-11-01), pages 1330, XP002048755, ISSN: 0190-5295
PHEBUS L A ET AL: "CHARACTERIZATION OF LY334370, A POTENT AND SELECTIVE 5-HT1F RECEPTOR AGONIST, IN THE NEUROGENIC DURAL INFLAMMATION MODEL OF MIGRAINE PAIN", SOCIETY FOR NEUROSCIENCE ABSTRACTS, vol. 22, no. 1/03, 1 November 1996 (1996-11-01), pages 1331, XP002048756, ISSN: 0190-5295

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