Title:
7-FLUORO-2, 3-DIDEHYDROSIALIC ACID AND INTERMEDIATE FOR SYNTHESIS THEREOF
Document Type and Number:
WIPO Patent Application WO/1995/032955
Kind Code:
A1
Abstract:
2, 7-Deoxy-7-fluoro-2, 3-didehydrosialic acid of general formula (IV) and intermediates therefor of general formulae (II) and (III); in formula (II), R represents aliphatic acyl; R1 represents lower alkyl; R2s represent each independently aliphatic or aromatic acyl; and R3 represents halogen; in formula (III), R represents aliphatic acyl; R1 represents lower alkyl; R2s represent each independently halogen, or aliphatic or aromatic acyl; and R4 represents thioacyl, thioalkyl or thioaryl; each being useful for developing practical medicines such as antiviral agents and preventives for viral diseases, and also as anticancer drugs and immunoregulators.
Inventors:
IIDA TAKAO (JP)
OHIRA YUTAKA (JP)
OHIRA YUTAKA (JP)
Application Number:
PCT/JP1995/000820
Publication Date:
December 07, 1995
Filing Date:
April 26, 1995
Export Citation:
Assignee:
DAIKIN IND LTD (JP)
IIDA TAKAO (JP)
OHIRA YUTAKA (JP)
IIDA TAKAO (JP)
OHIRA YUTAKA (JP)
International Classes:
C07D309/14; C07D309/28; C07D309/30; C07H13/04; (IPC1-7): C07D309/14; A61K31/35; C07D309/28; C07H5/06; C07H5/10
Other References:
J. CARBOHYDR. CHEM., 1 (3), (1993), p. 311-315.
CHEM. PHARM. BULL., 36 (5), (1988), p. 1872-1876.
AGRIC. BIOL. CHEM., 52 (5), (1988), p. 1209-1215.
CARBOHYDR. RES., 127 (2), (1984), p. 201-210.
CARBOHYDR. RES., 198 (2), (1990), p. 205-221.
CARBOHYDR. RES., 79 (1), (1980), p. 38-51.
See also references of EP 0711766A4
CHEM. PHARM. BULL., 36 (5), (1988), p. 1872-1876.
AGRIC. BIOL. CHEM., 52 (5), (1988), p. 1209-1215.
CARBOHYDR. RES., 127 (2), (1984), p. 201-210.
CARBOHYDR. RES., 198 (2), (1990), p. 205-221.
CARBOHYDR. RES., 79 (1), (1980), p. 38-51.
See also references of EP 0711766A4
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