Title:
7-SUBSTITUTED INDAZOLE DERIVATIVES AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/048471
Kind Code:
A1
Abstract:
Disclosed are a 7-substituted indazole derivative as shown in formula (I) or a pharmaceutically acceptable salt thereof, and a preparation method therefor, and the use of the same as a therapeutic agent, especially as aIRAK4 kinase inhibitor, wherein the definition of R1, R 2, R3, G and W in formula (I) are the same as the definition in the description.
Inventors:
ZHAI WENQIANG (CN)
LU YONGPING (CN)
ZHU YABO (CN)
YANG CUIXIA (CN)
LIN HAIMING (CN)
YE CHENG (CN)
QIAN WENJIAN (CN)
SHI ZHENGZHENG (CN)
HU TAISHAN (CN)
CHEN LEI (CN)
LU YONGPING (CN)
ZHU YABO (CN)
YANG CUIXIA (CN)
LIN HAIMING (CN)
YE CHENG (CN)
QIAN WENJIAN (CN)
SHI ZHENGZHENG (CN)
HU TAISHAN (CN)
CHEN LEI (CN)
Application Number:
PCT/CN2019/104281
Publication Date:
March 12, 2020
Filing Date:
September 04, 2019
Export Citation:
Assignee:
ZHEJIANG HISUN PHARM CO LTD (CN)
International Classes:
C07D231/56; A61K31/416; A61K31/4439; A61P15/00; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P35/00; A61P37/06; C07D401/12; C07D401/14; C07D405/14
Foreign References:
| CN106170486A | 2016-11-30 | |||
| CN107872977A | 2018-04-03 | |||
| TW201734004A | 2017-10-01 |
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (CN)
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